PROJECTS
Efficient, Fieldable DNA Purification Modules
Mobile BSL 2 Labs for Virus Detection
Nanopore-Based Sensor Technology for rapid DNA Analysis
Instant Anti-Infection Wound Care Dressing
GLYCOBLOCK™ : COVID-19 Neutralizing Mask Boosting Spray
- Technology Overview: This technology will advance a novel workflow and device for separation and recovery of human & plant DNA from complex samples for downstream DNA sequencing applications.
- Field of use: forensics, plant genetics, detection of biological agents (i.e. bacteria, viruses)
- Technology Readiness Level (TRL): 3
Mobile BSL 2 Labs for Virus Detection
- Technology Overview: Mobile BSL 2 labs are being developed in response to the existing COVID-19 pandemic and future viral outbreaks. Our labs aim to support existing and future demand for rapid, onsite virus detection using validated rt-PCR assays. Labs will be deployed for dedicated assay work to enable high throughout analysis and detection of a desired biological target (i.e. bacteria, virus). Mobile BSL 2 Labs will meet all state and federal specifications for CLIA approval.
- Field of use: detection of biological agents (i.e. bacteria, viruses) , COVID-19 detection
- Technology Readiness Level (TRL): 5
Nanopore-Based Sensor Technology for rapid DNA Analysis
- Technology Overview: This nanopore technology aims to advance a highly novel method to rapidly analyze DNA fragments for detection of biological organisms. The system consists of a novel nanopore microarrary sensor hardware to allow for rapid, parallel analysis of DNA fragments. Sensor hardware will be supported by proprietary software with DNA analysis capabilities enabling classification of detected biological targets.
- Field of use: detection of biological agents (i.e. bacteria, viruses)
- Technology Readiness Level (TRL): 1
Instant Anti-Infection Wound Care Dressing
- Technology Overview: This hydrogel material, from its dry state, can absorb enormous amount of aqueous solution, and incorporate materials with desired functions without toxicity issues. Such functions include 1) clotting of blood component to assist the natural hemostatic to stop the blood, 2) to prevent microbial growth or to kill bacteria and create a naturally sterile condition, 3) to soak up the secretion from the wound sites without binding to the regenerating growing tissue, and 4) to provide agents to assist a fast wound healing. While hemostatic agents exist in the market, the development of a functional hydrogel that provide a combined list of these functions is lacking.
- Field of use: wound dressing in the field
- Technology Readiness Level (TRL): 8
GLYCOBLOCK™ : COVID-19 Neutralizing Mask Boosting Spray
- Technology Overview: This innovative mask spray contains GLYCOBOCK™ , a natural surfactant that has been shown to bind COVID-19 Spike protein and inhibit viral entry into human cell. SARs-CoV-2 model studies using GLYCOBLOCK™ demonstrated 95% neutralizing of the virus. This mask spray is non-toxic, alcohol free, gluten free and contains all natural ingredients. More information can be found at www.glycoblock.com
- Field of use: neutralizing of SARs-CoV-2 virus (COVID-19) on masks and PPE material
- Technology Readiness Level (TRL): 9
PROJECT PARTNERING
Syracuse Biolabs (SBL) will work with it's research partners to secure seed, state and federal funding for innovative technologies. Priority will be given to projects and technologies capable of presenting positive preliminary data and commercial potential. For federal small business grant projects, SBL will actively assist and/or lead the project through pre-grant technology planning, grant preparation & submission, research management & reporting, and early commercial development. SBL will also provide the necessary research space ("Direct " support) and business infrastructure ("Indirect " support) to accommodate the scope of the project. Promising technologies may be considered for SBL seed funding to advance nascent biotechnology through proof of concept, improving the projects potential for follow-on funding.
AREAS OF INNOVATION
- Biological Sensing
- Real-Time Diagnostic and Detection
- Drug Screening/Discovery
- Therapeutic Development
- DNA/RNA High Throughput Sequencing
- Bioinformatics and Programming
- Forensic Technologies and Applications
- Molecular Modeling
- Chemical Synthesis
- Assay Development
- Liquid Biopsies
- Kit Chemistry/Reagents
- Mobile Lab Services